Modelling optional infinitive phenomena: A computational account of tense optionality in children’s speech

The Optional Infinitive hypothesis proposed by Wexler (1994) is a theory of children’s early grammatical development that can be used to explain a variety of phenomena in children’s early multi-word speech. However, Wexler’s theory attributes a great deal of abstract knowledge to the child on the basis of rather weak empirical evidence. In this paper we present a computational model of early grammatical development which simulates Optional Infinitive phenomena as a function of the interaction between a performance-limited distributional analyser and the statistical properties of the input. Our findings undermine the claim that Optional Infinitive phenomena require an abstract grammatical analysis

Modelling children's negation errors using probabilistic learning in MOSAIC.

Cognitive models of language development have often been used to simulate the pattern of errors in children’s speech. One relatively infrequent error in English involves placing inflection to the right of a negative, rather than to the left. The pattern of negation errors in English is explained by Harris & Wexler (1996) in terms of very early knowledge of inflection on the part of the child. We present data from three children which demonstrates that although negation errors are rare, error types predicted not to occur by Harris & Wexler do occur, as well as error types that are predicted to occur. Data from MOSAIC, a model of language acquisition, is also presented. MOSAIC is able to simulate the pattern of negation errors in children’s speech. The phenomenon is modelled more accurately when a probabilistic learning algorithm is used

Modeling children’s case marking errors with MOSAIC

We present a computational model of early grammatical development which simulates case-marking errors in children’s early multi-word speech as a function of the interaction between a performance-limited distributional analyser and the statistical properties of the input. The model is presented with a corpus of maternal speech from which it constructs a network consisting of nodes which represent words or sequences of words present in the input. It is sensitive to the distributional properties of items occurring in the input and is able to create ‘generative’ links between words which occur frequently in similar contexts, building pseudo-categories. The only information received by the model is that present in the input corpus. After training, the model is able to produce child-like utterances, including case-marking errors, of which a proportion are rote-learned, but the majority are not present in the maternal corpus. The latter are generated by traversing the generative links formed between items in the network

Piloting a manualised weight management programme (Shape Up-LD) for overweight and obese persons with mild-moderate learning disabilities: study protocol for a pilot randomised controlled trial

National obesity rates have dramatically risen over the last decade. Being obese significantly reduces life expectancy, increases the risk of a range of diseases, and compromises quality of life. Costs to both the National Health Service and society are high. An increased prevalence of obesity in people with learning disabilities has been demonstrated. The consequences of obesity are particularly relevant to people with learning disabilities who are already confronted by health and social inequalities. In order to provide healthcare for all, and ensure equality of treatment for people with learning disabilities, services must be developed specifically with this population in mind. The aim of this project is to pilot the evaluation of a manualised weight management programme for overweight and obese persons with mild-moderate learning disabilities (Shape Up-LD)

Modelling the impact of calorie‐reduction interventions on population prevalence and inequalities in childhood obesity in the Southampton Women’s Survey

Background: In the United Kingdom, rates of childhood obesity are high and inequalities in obesity have widened in recent years. Children with obesity face heightened risks of living with obesity as adults and suffering from associated morbidities. Addressing population prevalence and inequalities in childhood obesity is a key priority for public health policymakers in the United Kingdom and elsewhere. Where randomized controlled trials are not possible, potential policy actions can be simulated using causal modeling techniques. Objectives: Using data from the Southampton Women's Survey (SWS), a cohort with high quality dietary and lifestyle data, the potential impact of policy-relevant calorie-reduction interventions on population prevalence and inequalities of childhood obesity was investigated. Methods: Predicted probabilities of obesity (using UK90 cut-offs) at age 6–7 years were estimated from logistic marginal structural models adjusting for observed calorie consumption at age 3 years (using food diaries) and confounding. A series of policy-relevant intervention scenarios were modeled to simulate reductions in energy intake (differing in effectiveness, the targeting mechanisms, and level of uptake). Results: At age 6–7 years, 8.3% of children were living with obesity, after accounting for observed energy intake and confounding. A universal intervention to lower median energy intake to the estimated average requirement (a 13% decrease), with an uptake of 75%, reduced obesity prevalence by 1% but relative and absolute inequalities remained broadly unchanged. Conclusions: Simulated interventions substantially reduced population prevalence of obesity, which may be useful in informing policymakers

Recognising and responding to domestic violence: exploring the role of student dentists

The role of student dental practitioners in recognising, responding and appropriately managing domestic violence within a clinical setting in regional, rural and remote communities has not been investigated previously in Australia. Whilst extensive clinical training is provided to students throughout undergraduate dental degrees, anecdotal reports suggest that they feel ill-prepared for responding appropriately in both practice and the community to women who experience domestic violence. This presentation reports on an innovative partnership between Dentistry and Social Work at James Cook University and the Cairns Regional Domestic Violence Service to collaboratively address this problem through an educational intervention, which was evaluated by dental student researchers. The aim of the research was to explore dental students' perceptions of the effectiveness and value of the 'Recognise and Respond to Domestic Violence' educational intervention for their clinical placements and to inform dental curriculum design. A mixed methods approach was taken using pre and post intervention surveys and focus groups in order to identify and document undergraduate dental students' understanding, perceptions and preparedness in managing domestic violence clinically. The intervention involved a series of "Recognise and Respond to Domestic Violence" workshops delivered by expert facilitators for 234 Bachelor of Dental Surgery students in Clinical Years 3 – 5. Knowledge and perceptions of domestic violence before and after the workshops were compared and contrasted. Focus groups then enriched the evaluation data on the value, effectiveness and clinical application of the intervention. Findings indicated a significant increase in students' understanding, perceptions and theoretical knowledge regarding domestic violence. Students also reported that they were enabled to embed an awareness of domestic violence into their clinical assessment and patient management. Focus group data confirmed the useful nature of the knowledge gained in the workshops. However, the findings indicate that while recognition of domestic violence was achieved, further educational strategies are required to strengthen dental students' confidence in responding appropriately both within clinical practice and the wider community. Recommendations include embedding the domestic violence content into the undergraduate clinical curriculum. Further strengthening of dental students' capacity to respond to domestic violence should be developed across the clinical years through learning experiences that include simulation and role plays, which provide opportunities to practice techniques and employ strategies that were introduced in the workshops. Although the findings of this small study cannot be generalised, they suggest that this socially accountable, educational initiative would be valuable for other dental programs

Determinants of sleep quality in 5835 individuals living with and beyond breast, prostate, and colorectal cancer: a cross-sectional survey

Purpose: The present study aimed to quantify the level of sleep problems in 5835 breast, prostate, and colorectal cancer survivors, and explore a number of potential determinants of poor sleep quality in the present sample. BMI, diet, and physical activity were of particular interest as potential determinants. / Methods: Participants who completed the ‘Health and Lifestyle after Cancer’ survey were adults who had been diagnosed with breast, prostate, or colorectal cancer (mean time since cancer diagnosis was 35.5 months, SD=13.56). Sleep quality was assessed using the Pittsburgh Sleep Quality Index. BMI was calculated from self-reported height and weight. Participants were categorised as meeting/not meeting the World Cancer Research Fund (WCRF) recommendations for fibre, fruit and vegetables, added sugar, red meat, processed meat, fat, alcohol, and physical activity. Analyses accounted for demographic and clinical factors. / Results: Fifty-seven percent of those with sleep data were classified as poor sleepers (response rate 79%). Being female, having a higher number of cancer treatments, more comorbid conditions, and being more anxious/depressed increased the odds of being a poor sleeper. After adjustment for these factors, there were no associations between diet/alcohol/physical activity and sleep. However, BMI was associated with sleep. Individuals in the overweight and obese categories had 22% and 79% higher odds of being poor sleepers than individuals in the underweight/healthy weight category, respectively. / Conclusions: The findings suggest that there may be a need to develop sleep quality interventions for cancer survivors with obesity. Even after adjustment for multiple clinical and demographic factors, BMI (particularly obesity) was associated with poor sleep. Thus, researchers and health professionals should find ways to support individuals with overweight and obesity to improve their sleep quality

Allografts Surviving for 26 to 29 Years Following Living-Related Kidney Transplantation: Analysis by Light Microscopy, In Situ Hybridization for the Y Chromosome, and Anti-HLA Antibodies

We studied seven patients aged 14 to 40 years who received living-related kidney transplants and had allograft survivals of 26 to 29 years. The blood urea and creatinine were either within normal limits or marginally elevated. Histopathologic examination showed only mild mesangial expansion, interstitial fibrosis, and arteriosclerosis. Immunoperoxidase staining with anti-HLA antibodies or in situ hybridization with a Y chromosome probe showed persistence of donor tubular epithelium and vascular endothelium within the graft. Recipient-derived glomerular cells were seen in one case, and interstitial lymphocytic infiltrates were seen in all cases. A review of the clinicopathologic data available for these cases indicated that both central and peripheral immunologic mechanisms contributed to the maintenance of prolonged graft survival. This extended survival was independent of six antigen matching, downregulation of donor HLA antigen expression, and ingrowth of host epithelium/endothelium into the allograft. © 1994, National Kidney Foundation. All rights reserved. All rights reserved